Caution should be exercised when nystatin is prescribed for a nursing woman. It is not known whether nystatin is excreted in human milk. Nystatin cream should be prescribed for a pregnant woman only if the potential benefit to the mother outweighs the potential risk to the fetus. It also is not known whether this cream can cause fetal harm when used by a pregnant woman or can affect reproductive capacity. No studies have been performed to determine the mutagenicity of nystatin or its effects on male or female fertility.Īnimal reproduction studies have not been conducted with any nystatin cream. No long-term animal studies have been performed to evaluate the carcinogenic potential of nystatin. If there is a lack of therapeutic response, KOH smears, cultures, or other diagnostic methods should be repeated.Ĭarcinogenesis, Mutagenesis, Impairment of Fertility If symptoms of irritation develop, the patient should be advised to notify the physician promptly. Even if symptomatic relief occurs within the first few days of treatment, the patient should be advised not to interrupt or discontinue therapy until the prescribed course of treatment is completed.ģ. This medication is not for any disorder other than that for which it is prescribed.Ģ. The patient should be instructed to use these medications as directed (including the replacement of missed doses). Patients using these medications should receive the following information and instructions:ġ. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses. This resistance is lost when the antibiotic is removed. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. Generally, resistance to nystatin does not develop during therapy. On repeated subculturing with increasing levels of nystatin,Ĭandida albicans does not develop resistance to nystatin. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. krusei, Torulopsis glabrata, Tricophyton rubrum, T. In vitro against a wide variety of yeasts and yeast-like fungi, includingĬandida albicans, C. Nystatin is an antibiotic which is both fungistatic and fungicidal It is also important information to carry with you in case of emergencies.Nystatin is not absorbed from intact skin or mucous membrane. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Tell your doctor if your skin condition gets worse or does not go away. If you still have symptoms of infection after you finish the nystatin and triamcinolone, call your doctor. Ask your pharmacist any questions you have about refilling your prescription. Do not apply dressings, bandages, cosmetics, lotions, or other skin medications to the area being treated unless your doctor tells you.ĭo not let anyone else use your medication. Do not let nystatin and triamcinolone get into your eyes, nose, or mouth, and do not swallow it. This medication is for external use only. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. See the FDA's Safe Disposal of Medicines website ( ) for more information if you do not have access to a take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Instead, the best way to dispose of your medication is through a medicine take-back program. However, you should not flush this medication down the toilet. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Keep this medication in the container it came in, tightly closed, and out of reach of children.
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